NEUROMODULATION, ELECTROPHYSIOLOGY, NEUROCIRCUITS
Our research focuses on the study of cortical and subcortical brain circuit underlying behavior, by recording and modulating neural activity in various preclinical models. With a strong emphasis on functional and structural neuroplasticity, our lab combines in-vivo electrophysiological recordings with histological analyses to investigate key brain regions involved in physiological, neurological, and neuropsychiatric disorders.
We primarily aim to elucidate how brain activity can be modulated through non-invasive techniques such as transcranial direct current stimulation (tDCS) and repetitive transcranial magnetic stimulation (rTMS). In particular, we explore the therapeutic potential of tDCS, in models of neurological diseases such as brain ischemia, Alzheimer's disease, and Down syndrome, collaborating closely with other research groups all over Europe.Â
Overall, through an interdisciplinary approach, we integrate cutting-edge neuromodulatory technologies, experimental design, and behavioral analyses to advance basic neuroscience and clinical applications. This coordinated effort, supported by our state-of-the-art facilities and a vibrant research environment, drives our vision of contributing to transformative discoveries in brain research.
Our latest news:
Marco took part in the 12th Winter Seminar on Dementia and Neurodegenerative Disorders in Bressanone, presenting the lab work "Impaired prefrontal cortex-raphe circuit is associated with Alzheimer's disease cognitive impairments in the 3xTg mice: is it a breeding ground for tACS?".
The research, funded by Airalzh, explores the role of the prefrontal cortex-dorsal raphe circuit in Alzheimer's-related cognitive deficits and the potential of tACS as a therapeutic approach.
February 6th, 2025