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NEUROMODULATION, ELECTROPHYSIOLOGY, NEUROCIRCUITS
Our research focuses on the study of cortical and subcortical brain circuit underlying behavior, by recording and modulating neural activity in various preclinical models. With a strong emphasis on functional and structural neuroplasticity, our lab combines in-vivo electrophysiological recordings with histological analyses to investigate key brain regions involved in physiological, neurological, and neuropsychiatric disorders.
We primarily aim to elucidate how brain activity can be modulated through non-invasive techniques such as transcranial direct current stimulation (tDCS) and repetitive transcranial magnetic stimulation (rTMS). In particular, we explore the therapeutic potential of tDCS, in models of neurological diseases such as brain ischemia, Alzheimer's disease, and Down syndrome, collaborating closely with other research groups all over Europe.
Overall, through an interdisciplinary approach, we integrate cutting-edge neuromodulatory technologies, experimental design, and behavioral analyses to advance basic neuroscience and clinical applications. This coordinated effort, supported by our state-of-the-art facilities and a vibrant research environment, drives our vision of contributing to transformative discoveries in brain research.
Our latest news:
New fundings by Telethon
New fundings by Telethon
Fondazione Telethon has awarded funding to a research project involving the University of Verona aimed at identifying new therapeutic targets for a rare genetic disorder, primary autosomal recessive microcephaly-17 (Mcph17). The project was selected within the second edition of Telethon’s 2025–2027 funding call.
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February 9th, 2026
New preprint is out!
New preprint is out!
Anodal transcranial direct current stimulation promotes cortical myelin repair in a mouse model of focal demyelination by enhancing oligodendroglial survival, maturation, and remyelination when applied during the repair phase. Stimulation also increases myelin in the uninjured cortex and preserves interhemispheric motor connectivity, revealing a novel role of tDCS in myelin plasticity and supporting its therapeutic potential for myelin-related brain disorders.
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January 23rd, 2026
New paper alert!
New paper alert!
Selective activation of melatonin MT2 receptors with UCM924 alleviates MK-801–induced hyperactivity and social deficits in mice, enhancing prefrontal inhibitory interneuron activity without affecting dopaminergic neurons. While MT2 stimulation modulates cortical gamma oscillations, it fails to restore cognitive performance or network synchronization, indicating a selective impact on positive- and negative-like schizophrenia symptoms through non-dopaminergic mechanisms.
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January 20th, 2026
A visit from young scientists
In January, we welcomed the children of Class 2B from Guarino da Verona Primary School to our university and laboratory. Guided by the lab team, the students participated in hands-on activities that introduced them to the world of science and research, inspiring curiosity and excitement for scientific discovery.
January 18th, 2026
New paper alert!
New paper alert!
Combining anodal-transcranial direct current stimulation (A-tDCS) with low-intensity physical activity enhances structural and functional plasticity in the mouse motor cortex more than either intervention alone, highlighting the importance of brain state during stimulation and offering insights relevant to learning, memory, and neurological recovery.
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May 6th, 2025
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